OG Anunoby added 20 points and Deuce McBride had 16 for the Knicks, who had a 24-7 run starting late in the third quarter and extending into the fourth to turn a four-point deficit into a 105-92 advantage.
Kawhi Leonard scored 25 points for the Clippers, who lost for just the second time in nine games. James Harden had 23 points and nine assists after sitting out Monday against Golden State because of right shoulder soreness.
The Clippers raced to a 14-5 lead, but the Knicks answered with eight straight points and the game was close for the first three quarters. The Clippers were up 85-81 late in the third before the Knicks finished strong to take a 90-87 edge to the fourth.
Towns then started the period with a three-point play and follow shot, and later had four points in an 8-0 run that pushed a five-point lead to 105-92.
Ivica Zubac had 22 points and 11 rebounds for the Clippers, and John Collins added 18 points and 10 boards.
Up next
Clippers: Visit Brooklyn on Friday.
Knicks: Visit Phoenix on Friday to start a four-game road trip.
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AP NBA: https://apnews.com/hub/NBA