Home Team listed first.
Region 1
1 Lakewood St. Edward (10-1) vs. 8 Mentor (8-3) at Parma Byers Field
4 Westerville Central (10-1) vs. 5 Euclid (9-2) at Mansfield Arlin Field
2 Stow-Munroe Falls (11-0) vs. 7 Solon (9-2) at University of Akron InfoCision Stadium – Summa Field
3 Lewis Center Olentangy (10-1) vs. 6 Toledo Whitmer (9-2) at Tiffin Columbian Frost-Kalnow Stadium
Region 2
1 Colerain (10-1) vs. 9 St. Xavier (7-4) at Mason Dwire Field at Atrium Stadium
13 Hilliard Darby (9-2) vs. 5 Elder (8-3) at Dayton Welcome Stadium
2 Hilliard Davidson (10-1) vs. 10 Upper Arlington (8-3) at Hilliard Bradley Athletic Complex
3 Wayne (11-0) vs. 11 Springboro (9-2) at Centerville Stadium
Division II – Games at 7:30 p.m. Friday, Nov. 13
Home Team listed first.
Region 3
8 Macedonia Nordonia (8-3) vs. 5 Hudson (9-2) at Bedford Bearcat Stadium
7 Warren G. Harding (8-3) vs. 3 Mayfield (10-1) at Solon Stewart Field
Region 4
1 Grafton Midview (11-0) vs. 4 Cleveland Glenville (10-1) at Avon Lake Memorial Stadium
2 Perrysburg (11-0) vs. 3 Avon (10-1) at Sandusky Perkins Firelands Regional Medical Center Stadium
Region 5
1 Massillon Perry (9-2) vs. 5 Dresden Tri-Valley (10-1) at Dover Crater Stadium
2 Pataskala Licking Heights (10-1) vs. 3 Worthington Kilbourne (10-1) at New Albany Veterans Field
Region 6
1 La Salle (9-2) vs. 5 Lima Senior (9-2) at Kettering Fairmont Roush Stadium
2 Kings (10-1) vs. 3 Turpin (10-1) at West Chester Lakota West Firebird Field
Division III – Games at 7:30 p.m. Friday, Nov. 13
Home Team listed first.
Region 7
1 Akron Hoban (10-1) vs. 5 Louisville (10-1) at Uniontown Green Memorial Stadium
2 Akron St. Vincent-St. Mary (10-1) vs. 6 Chesterland West Geauga (10-1) at Ravenna Portage Community Bank Stadium
Region 8
1 Cleveland Benedictine (11-0) vs. 5 Bay Village Bay (10-1) at First Federal Lakewood Stadium
2 Toledo Central Catholic (9-2) vs. 3 Clyde (10-1) at Millbury Lake Community Stadium
Region 9
8 Col. Watterson (6-4) vs. 4 Jackson (10-1) at Chillicothe Herrnstein Field
2 Col. St. Francis DeSales (10-1) vs. 3 Zanesville (10-1) at Newark White Field
Region 10
1 Wapakoneta (11-0) vs. 4 Cin. Mt. Healthy (8-3) at Clayton Northmont Good Samaritan Stadium, Matt Dudon Memorial Field
2 Tippecanoe (10-1) vs. 3 Trotwood-Madison (8-3) at Huber Heights Wayne Good Samaritan Athletic Field at Heidkamp Stadium
Division IV – Games at 7 p.m. Saturday, Nov. 14
Region 11
1 Peninsula Woodridge (11-0) vs. 5 Youngstown Ursuline (6-5) at Hudson Memorial Stadium - Murdough Field
7 Parma Heights Holy Name (8-3) vs. 3 Mantua Crestwood (9-2) at Macedonia Nordonia Boliantz Stadium
Region 12
1 Columbus Bishop Hartley (7-3) vs. 5 Ottawa-Glandforf (8-3) at Bellefontaine AcuSport Stadium
7 Bellevue (9-2) vs. 6 Kenton Ridge (8-3) at Findlay Donnell Stadium
Region 13
1 Steubenville (10-0) vs. 5 Salem (10-1) at Minerva Dr. Robert H. Hines Stadium
2 Johnstown-Monroe (11-0) vs. 3 St. Clairsville (9-1) at Zanesville Sulsberger Stadium
Region 14
1 Fenwick (11-0) vs. 4 Alter (10-1) at West Carrollton DOC Stadium
2 Cin. Indian Hill (11-0) vs. 3 Clinton-Massie (10-1) at Mancuso Field at Cincinnati Princeton Stadium
Division V – Games at 7:30 p.m. Friday, Nov. 13
Region 15
1 Columbiana Crestview (9-2) vs. 5 Leavittsburg LaBrae (9-2) at Boardman New Spartan Stadium
2 Magnolia Sandy Valley (10-1) vs. 3 Canton Central Catholic (8-3) at Massillon Paul Brown Tiger Stadium
Region 16
1 Milan Edison (10-1) vs. 4 Swanton (10-1) at Tiffin Columbian Frost-Kalnow Stadium
7 Rossford (9-2) vs. 6 Doylestown Chippewa (9-2) at Kalahari Field at Huron Memorial Stadium
Region 17
1 Wheelersburg (11-0) vs. 4 West Lafayette Ridgewood (10-1) at Logan Chieftain Stadium
2 Chillicothe Zane Trace (11-0) vs. 3 Albany Alexander (10-1) at Waverly Raidiger Field
Region 18
1 Brookville (11-0) vs. 5 Greeneview (8-3) at Xenia Doug Adams Stadium
2 Cin. Hills Christian Academy (10-1) vs. 3 Coldwater (11-0) at Piqua Alexander Stadium, Purk Field
Division VI – Games at 7 p.m. Saturday, Nov. 14
Region 19
1 Kirtland (10-1) vs. 5 Brookfield (10-1) at Twinsburg Tiger Stadium
7 Smithville (8-3) vs. 6 Cuyahoga Heights (9-2) at Medina Highland Stadium - North Gateway Tire Field
Region 20
8 Delta (7-4) vs. 5 Van Buren (8-3) at Holland Springfield Community Stadium
2 Defiance Tinora (9-1) vs. 3 North Robinson Colonel Crawford (10-1) at Lima Spartan Stadium
Region 21
8 Fredericktown (9-2) vs. 4 Bainbridge Paint Valley (10-1) at Hamilton Township Alumni Stadium
2 Lucasville Valley (9-1) vs. 3 Grandview Heights (10-1) at Chillicothe Herrnstein Field
Region 22
1 Marion Local (10-1) vs. 5 West Liberty-Salem (9-2) at Wapakoneta Harmon Field
2 Mechanicsburg (11-0) vs. 3 Delphos Jefferson (10-1) at Sidney Memorial Stadium
Division VII – Games at 7:30 p.m. Friday, Nov. 13
Region 23
1 Warren John F. Kennedy (10-1) vs. 4 Toronto (10-1) at Austintown-Fitch Greenwood Chevrolet Falcon Stadium
2 Mogadore (10-1) vs. 3 Norwalk St. Paul (10-1) at Medina Ken Dukes Stadium
Region 24
1 McComb (10-1) vs. 4 Leipsic (6-5) at Findlay Donnell Stadium
7 Tiffin Calvert (6-5) vs. 3 Lucas (9-1) at First National Bank Field at Bellevue Athletic Facility
Region 25
1 Danville (11-0) vs. 4 Canal Winchester Harvest Prep (9-2) at Westerville Central Warhawk Field
2 Caldwell (10-1) vs. 3 Glouster Trimble (9-2) at Zanesville Maysville Athletic Complex
Region 26
1 Minster (9-2) vs. 4 DeGraff Riverside (10-1) at Sidney Memorial Stadium
7 Lehman Catholic (7-4) vs. 3 Fort Recovery (9-2) at Lima Spartan Stadium