Mechanicsburg’s Mack Delong caused a fumble and Kix Thiel returned it 27 yards for a TD. The Indians outgained the Bobcats (7-5) 415 yards to 162 yards. The Bobcats struggled on the ground, rushing for 25 yards on 33 carries as a team.
The Indians will face Covington (10-2) at 7 p.m. Friday at a site to be determined. The Buccaneers beat Chillicothe Southeastern 36-20 in the other semifinal game.
The Ohio High School Athletic Association will announce sites for regional final games on Sunday afternoon.
Mechanicsburg has advanced to the playoffs each of the last seven seasons, but is seeking its first state semifinal berth since 2013. Covington has made 19 playoff appearances since it last advanced to the state semifinals in 1985.