The Cincinnati Reds 16-0 loss to Jake Arrieta and the Chicago Cubs on Thursday was the most lopsided no-hit defeat in Major League Baseball since 1884, according to Ronald Liebman of SABR.org and confirmed by Dayton Daily News sports statistical expert Jonmarc Lippincott.
The worst no-hit loss in the 20th century was in 1905 when pitcher Frank Smith of the Chicago White Sox no-hit the Detroit Tigers in a 15-0 win. Jim Galvin of Buffalo won an 18-0 no-hitter against Detroit in 1884 - 132 years ago.
The Reds were last no-hit in the regular season on June 23, 1971 by Rick Wise of the Philadelphia Phillies, the longest streak in the majors and the second longest in history. Roy Halladay pitched a perfect game against the Reds in 2010, but it was in the postseason during National League Divsion Series playoffs.