This year will be a historic march as Vice President Mike Pence is expected to speak during the march. It is the first time a president or vice president has taken part.
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The president of the March for Life said that Pence is "a friend and champion of the pro-life cause his entire career," as a congressman, then Indiana governor, and currently as vice president, the AP reported.
Kellyanne Conway, Archbishop of New York Cardinal Timothy Dolan and Baltimore Ravens tight end Benjamin Watson will also be in attendance, according to a march press release.
Organizers said that the march will begin after a rally on the National Mall before protesters march to the Supreme Court.
This year's theme is the "Power of One," to show how individuals can make a difference fighting for lives, according to march organizers.
Park service officials and march organizers said they don't believe there will be violence during the march as seen during last week's Inauguration events, but are prepared in case of emergency, WRC reported.
The March for Life comes just under a week after the Women's March took over major cities across the world. The Women's March protested for abortion rights, among women's rights, WRC reported.
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