Ivey described the amount of drugs confiscated in the bust as "enough fentanyl to kill everyone in Brevard County," which has a population close to 600,000.
Investigators also seized guns and money as part of the investigation.
Sheriff's spokesman Tod Goodyear said almost 200 people have died in opiate-related incidents over the past two years in Brevard County, according to the newspaper.
"Many of these deaths are directly related to fentanyl, a powerful opioid that is 50 to 100 times more potent than morphine and 30 to 50 times more potent than heroin," Goodyear said.
Fentanyl is so powerful, it can incapacitate anyone who comes into contact with it because it can be absorbed through the skin or accidentally inhaled.