"Quite simply, we have found support for the existence of internal bathroom scales. The weight of the body is registered in the lower extremities. If the body weight tends to increase, a signal is sent to the brain to decrease food intake and keep the body weight constant," coauthor John-Olov Jansson said in a statement.
Researchers now want to further their investigations with hopes of yielding the same results for humans. If so, they believe they can help doctors find effective treatments for obesity.
“The mechanism that we have now identified regulates body fat mass independently of leptin,” coauthor Claes Ohlsson added. “And it is possible that leptin combined with activation of the internal body scales can become an effective treatment for obesity.”